Dyspepsia in Iran: SEPAHAN Systematic Review No. 3

Background: dyspepsia is an upper gastrointestinal tract syndromepresenting epigastric pain and discomfort, fullness sensation, earlysatiety, nausea, vomiting, and belching. the prevalence of dyspepsiahas been reported to be high all over the world. in this study, we reviewedstudies reporting the prevalence of dyspepsia in iran and discussedthe probable risk factors of dyspepsia to shed light on futureresearch on this topic.methods: the four electronic databases of pubmed, google scholar,iranmedex, and scientific information database were searched. thekeywords for the electronic search were “dyspepsia” and “iran”. amanual search of the reference lists of the selected articles was alsocarried out. two reviewers reviewed and identified articles independentlyand selected relevant studies based on our inclusion and exclusioncriteria.results: nine articles reporting the prevalence of dyspepsia in iranwere included. the reported prevalence ranged from 2.2% to 29.9%.the majority of studies have reported the prevalence of dyspepsia tobe higher in women.conclusion: dyspepsia seems to be highly prevalent in iran. consideringthe wide range of data reported in different studies, conductingfurther population-based studies is necessary to investigate the epidemiologyand risk factors of dyspepsia among iranians.