National Cholesterol Education Program Adult Treatment Panel III Versus International Diabetic Federation Definition of Metabolic Syndrome, Which One is Associated with Diabetes Mellitus and Coronary

Background: a cluster of risk factors for cardiovascular diseasesand type 2 diabetes mellitus, which occur together more often thanby chance alone, have been known as the metabolic syndrome.various definitions have been proposed by different organizationsover the past decade. this study was designed to evaluate a newdefinition of the metabolic syndrome for the prediction of diabetesmellitus among the iranian population.methods: this study was carried out in an urban population,aged 20 to 74 years, from yazd, a city in the center of iran. thestudy is a part of the phase i of yazd healthy heart program,that is, a community?based intervention study for the preventionof cardiovascular disease. the significance level has been definedas p < 0.05.results: prevalence of the metabolic syndrome by the nationalcholesterol education program adult treatment panel iii (ncepatp iii) criteria was 21.3 ± .017%, and by international diabetesfederation (idf) criteria it was 30.16 ± .02%. the multivariateanalysis showed that the most important relevant factors ofdiabetes mellitus were: increased age and metabolic syndrome byboth definitions of ncep and idf criteria, and also, the mostimportant relevant factors of stable angina were: increased age,male sex, and metabolic syndrome by only idf definitions, butthe ncep definition of the metabolic syndrome cannot predictdiabetes mellitus independent of age and sex.conclusion: this study showed that increased age and metabolicsyndrome are the most important relevant factors for diabetesmellitus, especially by using the idf criteria for definition of themetabolic syndrome.