Epidemiologic Evidence on Serum Adiponectin Level and Lipid Profile

The concentration of adiponectin, a hormone which is secreted fromadipose tissue, is inversely correlated with body fat mass. this hormonehas anti inflammatory and anti atherogenic properties. its concentrationreduces in metabolic syndrome and cardiovascular diseases. this studyreviews the evidence on the relationship between serum adiponectinconcentration and lipid profile. in this study former clinical trials, crosssectional and prospective studies have been reviewed. the pubmedsearch engine has been used to find related research for the topic byconsidering dyslipidemia, total cholesterol (tc), high and low densityprotein (hdl and ldl), triglyceride (tg), lipid profile (lp) andadiponectin as the key words. finally, 25 articles were recruited to reviewin the present article. serum adiponectin level was positively correlatedwith plasma hdl cholestrol concentrations. there was a significantinverse relationship between plasma triglyceride and serum adiponectin.an inverse correlation between very low density lipoprotein (vldl)and ldl levels and adiponectin was reported from the studies. so,adiponectin has an important role in the metabolism of lipid profileincluding hdlc.