Hepatic Necrosis: A Main Presentation of Systemic Lupus Erythematosus in a Previously Healthy Woman

Systemic lupus erythematosus (sle) is a chronic inflammatory disease of unknown cause. in this study, we report a case of sle that was presented with persistent vomiting and liver involve- ment. to our knowledge, this is the first description of a patient with hepatic necrosis as the initial presentation of sle in a pre- viously healthy woman without any significant past medical history. in the literature, we found few cases of sle with liver necrosis. in addition, all the cases found had a past medical his- tory of a missed abortion or other complications of the disease. therefore, if a young woman presents hepatic necrosis with a background of a previously missed abortion, it is better to per- form anti-nuclear antibody (ana) and anticardiolipin antibody tests as a preventive method for early diagnosis and early treat- ment.