Assessment of Insulin Resistance with Two Methods: HOMA-IR and TyG Index in Iranian Obese Women

Objective: the aim of the present study is assessment of insulin resistance (ir) in obese women by tyg-index and compared with the homa-ir index. materials and methods: this cross-sectional study was performed on 61 obese women aged 18-45 years. weights, height, waist circumference (wc) were measured and body mass index (bmi) was calculated and recorded. a sample of fasting serum was collected to determine the glucose, triglyceride, insulin, total cholesterol, hdl-c and ldl-c concentration. homa-ir and tyg-index were calculated as markers of insulin resistance.results: the mean age of the precipitants was 32.5 ±0.79 years old and the mean weight was 86.0±1.7 kg. the number of people with ir who determined by homa and tyg index were 21(34%) and 36(61%), respectively. there was a significant relationship between homa-ir and tyg index, r= 0.044 (p < 0.001).conclusion: tyg index represents a useful and accessible tool for assessment of ir instead homa_ir in iranian population, but more researches with greater sample size and via gold standard lab test need to evaluate the specificity and sensitivity of this new method.