clinical manifestations and outcomes of covid-19 in diabetes mellitus people, yazd, iran-2021

Objective: diabetes mellitus is reported to be the third most prevalent comorbidity with covid-19, after cardio‐cerebrovascular disease and hypertension. furthermore, diabetes increases the likelihood of admission to the hospital and intensive care unit and death from covid-19. the aim of the present study was to compare the clinical manifestations and outcomes of covid-19 in diabetic versus non-diabetic inpatients.materials and methods: the medical records of 6525 patients with definitive diagnosis of covid-19 were obtained from the reference covid-19 diagnosis laboratory from january to july 2021 in yazd, iran. patients were investigated for data on onset, clinical history, and fatality rate. covid-19-related death was defined as positive rt-pcr in at least one of three nasal samples. data were analysed using spss 24.results: among inpatients, 21.2% were diabetic. the mean ages of diabetic and non-diabetic patients were 64.45 (±13.87) and 52.98 (±20.36) years, respectively. diabetics were more likely to be admitted to the intensive care unit (6.8% vs. 5%, p= 0.02) and the fatality rate was higher among them than non-diabetics (22.6% vs. 12%, p< 0.001). in diabetics, the mean age of non-survivors was lower than that of survivors (62.57 vs. 70.48, p= 0.0001) and the frequency of death was higher among men than women (53% vs. 47.5%, p= 0.045). generally, diabetes has the strongest association with covid-19 death (p= 0.0001). conclusion: diabetic patients experience more adverse outcomes because of covid-19. these findings indicate the need for special attention in relation to prevention treatment against covid-19 in patients with diabetes.