serum chromium is inversely correlated with the carotid intima– media thickness in type 2 diabetic subjects

Objective: the aim of this study was to determine and correlate the serum chromium in carotid intima - media thickness (cimt) in type 2 diabetes mellitus (t2dm) subjects.materials and methods: the present case – control study included 40 healthy controls and 45 t2dm subjects that were selected through non-probability (purposive) sampling by prior inclusion and exclusion criteria. serum chromium (cr) was detected and measured on inductively coupled “plasma optical emission spectrophotometer” (icp- oes)- carotid artery was examined with a 7.5-mhz linear-array transducer (siemens acuson x300) sonography. data was analyzed by student’s t test and chi square test in the spss 22.0 (usa). linear regression model was used for predicting carotid intima media thickness. level of confidence interval of statistical significance was 95% (p≤ 0.05).results: serum cr in controls and cases was noted 0.873 (± 0.162) and 0.281 (± 0.240) µg/ml (p= 0.001). serum cr proved negative correlation with random blood sugar (r= -0.145, p= 0.185), hba1c (r= -0.145, p= 0.0001) and cimt (r= -0.730, p= 0.0001).  multiple regression analysis model showed significant association of serum cr (r= -0.730, p< 0.0001) and hba1c (r= 0.754, p< 0.0001) with the cimt.conclusion: the present study reported serum cr was inversely correlated with the carotid intima - media thickness that is a marker of atherosclerosis. cr supplements may be advised to diabetics in clinical management.