kk college of pharmacy, gerugambakam, chennai, india.

Objective: this study aimed to conduct a systematic review about diabetes mellitus and covid-19 severity, management, and mortality.materials and methods: thirteen studies were included in this review, comprising a total of 1155 covid-19 patients with diabetes mellitus as a significant comorbidity. data regarding patient demographics and the prevalence of comorbidities, including smoking, hypertension, cardiovascular disease, chronic kidney disease, and chronic liver disease, were collected.results: among covid-19 patients with diabetes mellitus, the majority were male (57.1%) compared to females (42.9%). the prevalence of comorbidities in covid-19 are varied, with smokers accounting for 1-12.6%, hypertension ranging from 8-41.6%, diabetes mellitus ranging from 7.4-70.8%, cardiovascular disease ranging from 1.6-23.0%, chronic kidney disease ranging from 0.7-2.9%, and chronic liver disease ranging from 0.5-4.6%. in comparison to covid-19 patients without diabetes, a higher proportion of patients with diabetes mellitus were admitted to the intensive care unit (36.8%). among covid-19 patients with diabetes mellitus, the survival rate was significantly higher at 62.2% compared to a lower rate of 13.4% observed among non-survivors with diabetes mellitus.conclusion: this systematic review emphasizes the significance of diabetes mellitus as a comorbidity in covid-19 patients, increasing the risk of icu admission. these findings emphasize the importance of identifying and effectively managing diabetes mellitus as a comorbidity in covid-19 patients to enhance overall outcomes.