improvement of glucose homeostasis in response to short-term aerobic training in middle-aged men with abdominal obesity

Objective: overweight and obesity is associated with insulin resistance and is the most important risk factor of type 2 diabetes (t2dm). in present study, we assessed glycemic profile and insulin resistance response to a short term aerobic training in middle-aged men with abdominal obesity. materials and methods: the subjects included 28 abdominally obese (waist circumference≥102cm) middle-aged men (39 ± 5 year) that were divided into exercise (n=14) or control (n=14) groups by randomly. exercise subject were completed a short-term aerobic training at 55-70 % of maximal heart rate (6 weeks, 3 times / weekly) and control subjects remained no training. pre-training and post-training of anthropometrical markers, fasting glucose, hemoglobin (hba1c), insulin and insulin resistance were measured of 2 groups and compared by independent – paired t test (spss, version 22.0). results: aerobic exercise resulted in a significant decrease in glucose level (114 ± 13 versus 101 ± 11 mg/dl, p: 0.009) and hba1c (6.14 ± 1.11 versus 4.91 ± 1.23, p: 0.021) in exercise group. but no significant changes were observed in insulin (8.31 ± 4.12 versus 8.29 ± 3.21, p: 0.119) and insulin resistance (2.34 ± 0.51 versus 2.07 ± 0.59, p: 0.073) in exercise groups. conclusion: based on our finding, aerobic training independent of insulin function is associated with improved glucose in middle-aged obese men and this improvement can be attributed to other changes caused by exercise that requires further study in this area.