effect of vitamin c therapy on serum parameters in patients with type 2 diabetes mellitus: clinical trial

Objective: diabetes mellitus (dm) is a leading cause of morbidity and death worldwide. dm will affect 570.9 million people worldwide by 2025. the usefulness of vitamin c in improving diabetes control has been a point of contention.materials and methods: this clinical-trial double-blind study with control groups was conducted on 164 patients with type 2 diabetes mellitus (t2dm). the intervention group received 1000 mg of oral vitamin c daily, and a placebo was administered to the controls. to analyze the obtained data, one-way anova was used in spss software (version 20). a p< 0.05 was considered statistically significant.results: fasting blood sugar (fbs), hemoglobin a1c (hba1c), triglyceride (tg), and high-density lipoprotein (hdl) were improved significantly in the intervention group (p< 0.05), while the low-density lipoprotein (ldl) and cholesterol were unaffected (p> 0.05). hba1c and ldl levels in the control group increased significantly (p< 0.05). meanwhile, this group’s hdl levels decreased considerably.conclusion: our findings support the consumption of vitamin c to complement the primary treatment for dm. according to our results, vitamin c provides a clear benefit over a placebo in the treatment of diabetic patients’ serum parameters.