benign mesenchymal hepatic tumors in camels (camelus dromedarius)

Benign tumors in liver are rare and appear not to have been previously reported in camel (camelus dromedarius). this study describes histopathologic characteristics of lipoma, cavernous hemangioma and leiomyoma in the liver of dromedary camels. seventy livers of dromedary camels which were slaughtered for human consumption were collected from july to november 2011 from the north east of iran and they had macroscopic lesions and all of them were studied histopathologically. microscopic examination revealed different metaplastic and neoplastic lesions in the liver of the camels. lipoma (with multiple large vacuolated cells), cavernous hemangioma (with large lakes filled with oval erythrocytes) and leiomyoma (with homogenous intense eosinophilic spindle cells) were diagnosed as benign tumors. the relatively high occurrence of these mesenchymal neoplastic lesions may be due to some metabolic imbalances and some toxicosis in dromedary camels which live in the deserts. also, metaplastic changes are the causes of lipoma. according to the literature, this is the first report of hepatic cavernous hemangioma and leiomyoma in camels (camelus dromedarius).

ﺗﻮﻣﻮرﻫﺎی ﺧﻮش ﺧﯿﻢ ﻣﺰاﻧﺸﯿﻤﯽ ﮐﺒﺪ درﺷﺘﺮ ﯾﮏ ﮐﻮﻫﺎﻧﻪ

ﺗﻮﻣﻮرﻫﺎی ﺧﻮش ﺧﯿﻢ در ﮐﺒﺪ ﻧﺎدر ﻣﯽﺑﺎﺷﻨﺪ و در ﮐﺒﺪ ﺷﺘﺮ ﮔﺰارش ﻧﺸﺪه اﺳﺖ .اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺑﻪ ﺷﺮح ﻣﺸﺨﺼﺎت ﻫﯿﺴـﺘﻮﭘﺎﺗﻮﻟﻮژی ﻟﯿﭙـﻮم، ﻫﻤـﺎﻧﮋ ﯾﻮم از ﺷﻤﺎل ﺷﺮﻗﯽ 1390 ﻏﺎری و ﻟﯿﻮﻣﯿﻮم در ﮐﺒﺪ ﺷﺘﺮان ﻣﯽﭘﺮدازد .ﻫﻔﺘﺎد ﮐﺒﺪ ﺷﺘﺮ ﮐﻪ ﺑﻪ ﻣﻨﻈﻮر ﻣﺼﺮف اﻧﺴﺎﻧﯽ ﻣﻮرد ﮐﺸﺘﺎر ﻗﺮار ﮔﺮﻓﺘﻨﺪ از ﺗﯿﺮ ﺗﺎ آﺑﺎن ﻣﺎه اﯾﺮان ﺟﻤﻊآوری ﺷﺪﻧﺪ و آن ﻌﺎت ﻣﺎﮐﺮوﺳـﮑﻮﭘﯽ ﺑﻮدﻧـﺪ و ﺗﻤـﺎﻣﯽ ﮐﺒـﺪﻫﺎ از ﻧﻈـﺮ ﻫﯿﺴـﺘﻮﭘﺎﺗﻮﻟﻮژی ﻣـﻮرد ﻣﻄﺎﻟﻌـﻪ ﻗـﺮار ﮔﺮﻓﺘﻨـ ﺪ ﻫﺎ دارای ﺿـﺎﯾ .ﺑﺮرﺳـﯽ ،( ﻫﯿﺴﺘﻮﭘﺎﺗﻮﻟﻮژی ﻣﻮﯾﺪ ﺗﻐﯿﯿﺮات ﻣﺘﺎﭘﻼﺳﺘﯿﮏ و ﻧﺌﻮﭘﻼﺳﺘﯿﮏ ﻣﺨﺘﻠﻒ در ﮐﺒﺪ ﺷﺘﺮان ﺑﻮد .ﻟﯿﭙﻮم )ﻫﻤﺮاه ﺑﺎ ﺗﻌـﺪاد ﻣﺘﻌـﺪدی ﺳـﻠﻮ لﻫـﺎی ﺑـﺰرگ واﮐﻮﺋﻠـ ﻪ ﻫﻤﺎﻧﮋﯾﻮم ﻏﺎری )ﻫﻤﺮاه ﺑﺎ درﯾﺎﭼﻪﻫﺎی ﺑﺰرگ ﻣﻤﻠﻮ از ارﯾﺘﺮوﺳﯿﺖﻫﺎی ﺑﯿﻀـﯽ ﺷـﮑ ﻞ (و ﻟﯿﻮﻣﯿـﻮم )ﻫﻤـﺮاه ﺑـﺎ ﺳـﻠﻮ لﻫـﺎی دوﮐـﯽ ﺷـﮑﻞ ﯾـﮏ دﺳـﺖ، اﺋﻮزﯾﻨﻮﻓﯿﻠﯿﮏ و ﻓﺸﺮده (ﺑﻪ ﻋﻨﻮان ﺗﻮﻣﻮرﻫﺎی ﺧﻮش ﺧﯿﻢ ﺗﺸﺨﯿﺺ داده ﺷﺪﻧﺪ .ﺷﯿﻮع ﺑﻪ ﻧﺴﺒﺖ ﺑﺎﻻی اﯾﻦ ﺟﺮاﺣﺎت ﻧﺌﻮﭘﻼﺳﺘﯽ ﻣﺰاﻧﺸﯿﻤﯽ ﻣﻤﮑﻦ اﺳﺖ ﺑﻪ ﻋﻠﺖ ﺑﺮﺧﯽ ﺑﯿﻤﺎریﻫﺎی ﻣﺘﺎﺑﻮﻟﯿﮑﯽ و ﯾﺎ ﻣﺴﻤﻮﻣﯿﺖ در ﺷﺘﺮان ﺑﺎﺷﺪ ﮐﻪ در ﺻﺤﺮا زﻧﺪﮔﯽ ﻣﯽﮐﻨﻨﺪ .ﻫﻤﭽﻨﯿﻦ ﺑﺮﺧـﯽ ﺗﻐﯿﯿـﺮات ﻣﺘﺎﭘﻼﺳـﺘﯽ ﻧﯿـﺰ ﻣـ ﯽﺗﻮاﻧـﺪ ﻣﺴﺒﺐ ﻟﯿﭙﻮم ﺑﺎﺷﺪ.ﺑﺮ اﺳﺎس ﺟﺴﺘﺠﻮﻫﺎی ﺻﻮرت ﮔﺮﻓﺘﻪ اﯾﻦ اوﻟﯿﻦ ﮔﺰارش ﻫﻤﺎﻧﮋﯾﻮم ﻏﺎری و ﻟﯿﻮﻣﯿﻮم در ﮐﺒﺪ ﺷﺘﺮان ﻣﯽﺑﺎﺷﺪ.