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Diagnostic value of interferon-c in the peripheral blood and the saliva of patients with oral lichen planus
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نویسنده
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Lotfi Ranya ,Imam Adel ,El-Mofty Mohamed ,Gareeb Maha
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منبع
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journal of the egyptian women's dermatologic society - 2014 - دوره : 11 - شماره : 1 - صفحه:24 -27
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چکیده
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Background the exact etiology of oral lichen planus (olp) remains obscure. t helper 1 cellassociated cytokines and chemokines have been implicated in the pathogenesis. among these cytokines, interferon-g (ifn-g) has been studied more extensively. objective the purpose of this study was to measure the level of ifn-g in peripheral blood and whole unstimulated saliva (wus) of olp patients to assess their diagnostic value. patients and methods ifn-g was measured simultaneously in serum and salivary (wus) samples of 30 olp patients and 30 healthy control individuals using enzyme-linked immunosorbent assay technique. results a significantly higher mean ifn-g in the saliva was found among olp cases compared with healthy control individuals, and the mean salivary ifn-g was significantly higher than that in the peripheral blood of cases. conclusion ifn-g in wus has a diagnostic value in olp lesions.
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کلیدواژه
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enzyme-linked immunosorbent assay ,interferon-g ,oral lichen planus ,peripheral blood ,saliva
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آدرس
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Ain Shams University, Department of Dermatology and Venereology, Egypt, Ain Shams University, Department of Dermatology, Egypt, Ain Shams University, Department of Oral Medicine, Periodontology and Oral Diagnosis, Egypt, Ain Shams University, Department of Dermatology and Venereology, Egypt
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Authors
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