Mitral valve replacement in systemic lupus erythematosus associated Libman-Sacks endocarditis

Libman-sacks endocarditis,first discovered in 1924,is a cardiac manifestation of systemic lupus erythematosus (sle). valvular involvement has been associated with sle and antiphospholipid syndrome (aps). mitral valve,especially its posterior leaflet,is most commonly involved.we report a case of a 34 year old woman with antiphospholipid antibody syndrome and sle,who presented with mitral valve regurgitation. the patient underwent a prosthetic mitral valve replacement,with no followup complications.we suggest mechanical valve replacement employment in the management of mitral regurgitation in libman-sacks endocarditis,in view of the recent medical literature and our own case report. © 2015 the authors.