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DABCO catalyzed rapid one-pot synthesis of 1,4-dihydropyrano [2,3-c] pyrazole derivatives in aqueous media
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نویسنده
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waghmare a.s. ,pandit s.s.
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منبع
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journal of saudi chemical society - 2017 - دوره : 21 - شماره : 3 - صفحه:286 -290
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چکیده
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A simple and efficient protocol is developed for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives by a one pot,four component reaction of ethylacetoacetate,hydrazine hydrate,malanonitrile and various aldehydes in the presence of a catalytic amount of dabco in aqueous medium. this method provides several advantages such as high yield,shorter reaction time,mild reaction condition,operational simplicity,easy work-up procedure with environment friendly nature and purification of products by non-chromatographic methods has been developed. © 2015 king saud university
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کلیدواژه
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Aqueous medium; DABCO; Ethylacetoacetate; Multicomponent reaction; Pyrano[2 ,3-c]pyrazole
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آدرس
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post graduate and research centre,department of chemistry,padmashri vikhe patil college of arts,science and commerce,pravaranagar,ahmednagar, India, post graduate and research centre,department of chemistry,padmashri vikhe patil college of arts,science and commerce,pravaranagar,ahmednagar, India
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Authors
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