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Synthesis and biological evaluation of fluorine substituted pyrazolo[4,3-e][1,2,4]triazines as purine analogues
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نویسنده
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abdel-rahman r.m. ,angawi r.f. ,al-mehmadi a.r.
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منبع
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journal of saudi chemical society - 2017 - دوره : 21 - شماره : 4 - صفحه:495 -503
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چکیده
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Some more new fluorine substituted pyrazolo[4,3-e][1,2,4]triazine derivatives (2–5),7,10,14,17 have been synthesized derived from hydrazinolysis of n-acyl/aroyl/dithioic formamido-2,3-dimethyl-1-phenyl-pyrazolo-5-ones which are obtained from 4-aminoantipyrine 1. the enzymatic assays (cellobaise activity) of the new products have been evaluated. © 2016
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کلیدواژه
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4-Aminoantipyrine; Cellobaise activity; Fluorinated pyrazolotriazines; Purine analogues
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آدرس
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department of chemistry,faculty of science,king abdulaziz university, Saudi Arabia, department of chemistry,faculty of science,king abdulaziz university, Saudi Arabia, department of chemistry,faculty of science,king abdulaziz university, Saudi Arabia
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Authors
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