Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics

Dibenzobarallene was used as a key intermediate for the synthesis of 2-(3-hydroxy-2-naphthoyl)-3,4,4a,5,10,10a-hexahydro-1h-5,10-benzenobenzo[g]phthalazine-1,4-dione (. 2). the previous compound was coupled with the appropriate diazonium chloride to give the corresponding 4-arylazo-2-naphthol derivatives 3a-. l. also,nitration,nitrosation and bromination of compound 2 afforded the corresponding nitro,nitroso and bromo derivatives 4-. 6,respectively. the synthesized compounds were established and evaluated as antibacterial agents. the results showed clearly that compounds 2,3a,3c,3d,3g,3i,4,5 and 6 exhibited interesting high activities compared with reference drugs. also,these compounds were applied to polyester as disperse dyes in which their color measurement and fastness properties were evaluated. © 2012 production and hosting by elsevier b.v.