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An efficient one-pot three-component synthesis of α-amino nitriles via Strecker reaction catalysed by bismuth(III) nitrate
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نویسنده
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sheik mansoor s. ,aswin k. ,logaiya k. ,sudhan s.p.n.
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منبع
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journal of saudi chemical society - 2016 - دوره : 20 - شماره : Supplement 1 - صفحه:S202 -S210
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چکیده
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A convenient and efficient one-pot method for the synthesis of a variety of α-amino nitriles from aldehydes,amines and trimethylsilyl cyanide (tmscn) in the presence of a catalytic amount of bi(no3)3 at room temperature in acetonitrile (mecn) is described. the significant features of this method are simple work-up procedure,inexpensive and non-toxic catalyst,shorter reaction times and excellent product yields. the catalyst bi(no3)3 can be reused. the reusability of the catalyst has been studied for the synthesis of various amino nitriles. © 2012
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کلیدواژه
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Amino nitriles; Bismuth nitrate; One-pot synthesis; Strecker reaction
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آدرس
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research department of chemistry,c. abdul hakeem college,melvisharam, India, research department of chemistry,c. abdul hakeem college,melvisharam, India, research department of chemistry,c. abdul hakeem college,melvisharam, India, research department of chemistry,c. abdul hakeem college,melvisharam, India
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Authors
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