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Synthesis,and antimicrobial evaluation of new pyridine imidazo [2,1b]-1,3,4-thiadiazole derivatives
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نویسنده
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bhardwaj v. ,noolvi m.n. ,jalhan s. ,patel h.m.
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منبع
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journal of saudi chemical society - 2016 - دوره : 20 - شماره : Supplement 1 - صفحه:S406 -S410
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چکیده
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With the aim of producing new biologically active compounds,a series of new pyridine imidazo [2,1b]-1,3,4-thiadiazole derivatives 4(a–k) were synthesized. all the compounds were characterized via ir,1h-nmr and mass spectral studies. the antimicrobial activity of newly synthesized compounds against various bacteria; bacillus pumillus,staphylococcus aureus,vibrio cholera,escherichia coli,proteus mirabilis,pseudomonas aeruginosa,and fungi; candida albicans were evaluated. among the compounds tested,4(a),4(b),4(f),4(h) and 4(k) exhibited good antimicrobial activity while others responded moderately with reference to standard drugs ampicillin and amphotericin b. © 2013
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کلیدواژه
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Antimicrobial activity; Pyridine Imidazo-thiadiazole; Synthesis
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آدرس
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department of biotechnology,bioinformatics and pharmacy,jaypee university of information technology,waknaghat,solan, India, department of pharmaceutical chemistry,shree dhanvantary pharmacy college,kim (surat) 394110, India, asbasjsm college of pharmacy,department of pharmaceutical chemistry,bela (ropar) 140111, India, department of pharmaceutical chemistry,r.c. patel institute of pharmaceutical education and research,shirpur (dhule), India
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Authors
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