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Synthesis,characterization and antimicrobial activity of some novel 4-(4-(arylamino)-6-(piperidin-1-yl)-1,3,5-triazine-2-ylamino)-N-(pyrimidin-2-yl)benzenesulfonamides
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نویسنده
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desai n.c. ,makwana a.h. ,senta r.d.
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منبع
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journal of saudi chemical society - 2016 - دوره : 20 - شماره : 6 - صفحه:686 -694
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چکیده
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As a part of our quest for the synthesis of new bioactive heterocyclic compounds,in our present work we have synthesized a series of 4-(4-(arylamino)-6-(piperidin-1-yl)-1,3,5-triazine-2-ylamino)-n-(pyrimidin-2-yl)benzenesulfonamide (3a–o) derivatives. the newly synthesized compounds were screened for their in vitro antimicrobial activity. compounds 3c,3n and 3o exhibited significant antimicrobial activity on several strains of microbes. the structures of newly synthesized compounds were elucidated by ir,1h nmr,13c nmr and mass spectral analysis. © 2015 the authors
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کلیدواژه
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5-Triazine; Antimicrobial activity; Benzenesulfonamide; Cyanuric chloride; Piperidine; Pyrimidine
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آدرس
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division of medicinal chemistry,department of chemistry,(ugc non-sap & dst-fist sponsored),maharaja krishnakumarsinhji bhavnagar university,mahatma gandhi campus, India, xrf,st. xavier's college,ahmedabad, India, division of medicinal chemistry,department of chemistry,(ugc non-sap & dst-fist sponsored),maharaja krishnakumarsinhji bhavnagar university,mahatma gandhi campus, India
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Authors
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