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One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
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نویسنده
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mohammadi ziarani g. ,hosseini nasab n. ,rahimifard m. ,abolhasani soorki a.
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منبع
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journal of saudi chemical society - 2015 - دوره : 19 - شماره : 6 - صفحه:676 -681
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چکیده
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A simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil,various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized sba-15 (sba-pr-so3h) is described. some of synthesized pyrido[2,3-d]pyrimidines showed antimicrobial activities against some fungi and gram positive and negative bacteria. © 2014 .
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کلیدواژه
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6-Amino uracil; Aldehydes; Functionalized SBA-15; Malononitrile; Multicomponent reaction; Solvent free
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آدرس
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alzahra university, ایران, alzahra university, ایران, alzahra university, ایران, shahid beheshti university, ایران
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Authors
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