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Synthesis of novel dipodal-benzimidazole,benzoxazole and benzothiazole from cyanuric chloride: Structural,photophysical and antimicrobial studies
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نویسنده
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padalkar v.s. ,gupta v.d. ,phatangare k.r. ,patil v.s. ,umape p.g. ,sekar n.
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منبع
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journal of saudi chemical society - 2014 - دوره : 18 - شماره : 3 - صفحه:262 -268
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چکیده
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In the present study,new benzimidazole,benzoxazole and benzothiazole derivatives were prepared and screened for antimicrobial activity. the structure of 4,4'-((6-(4-(diethylamino)phenyl)-1,3,5-triazine-2,4-diyl)bis(oxy))dibenzaldehyde (dipod) 5 was established from p-hydroxy benzaldehyde 4 and 4-(4,6-dichloro-1,3,5-triazin-2-yl)-n,. n-diethylaniline 3. the reaction of dipod 5 with different o-phenylenediamine or o-amino phenol or o-amino thiophenol in ethanol gave benzimidazole,benzoxazole and benzothiazole 7. novel heterocycles showed excellent broad-spectrum antimicrobial activity against bacterial strain (escherichia coli,staphylococcus aureus) and fungal strain (candida albicans,aspergillus niger) cultures. activity data was compared with standard streptomycin and fluconazole drug. photophysical and thermal properties of synthesized compounds were also studied. © 2011.
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کلیدواژه
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Antimicrobial study; Benzimidazole; Cyanuric chloride; Photo-physics; Thermal stability; Triazine
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آدرس
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department of intermediate and dyestuff technology,institute of chemical technology (formerly udct),n.p. marg,matunga,mumbai 400 019, India, department of intermediate and dyestuff technology,institute of chemical technology (formerly udct),n.p. marg,matunga,mumbai 400 019, India, department of intermediate and dyestuff technology,institute of chemical technology (formerly udct),n.p. marg,matunga,mumbai 400 019, India, department of intermediate and dyestuff technology,institute of chemical technology (formerly udct),n.p. marg,matunga,mumbai 400 019, India, department of intermediate and dyestuff technology,institute of chemical technology (formerly udct),n.p. marg,matunga,mumbai 400 019, India, department of intermediate and dyestuff technology,institute of chemical technology (formerly udct),n.p. marg,matunga,mumbai 400 019, India
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Authors
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