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QSAR studies on anti-apoptotic Bcl-2 protein inhibitors
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نویسنده
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Srivastava A. K. ,Srivastava Akanchha ,Archana ,Jaiswal Meetu ,Nath Arpita
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منبع
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journal of saudi chemical society - 2009 - دوره : 13 - شماره : 3 - صفحه:259 -262
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چکیده
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Qsar studies on a series of inhibitors for anti-apoptotic bcl-2 proteins based on bhi-1 were performed the activities are found to correlate well with some topological parameters and steric parameters. the results are critically discussed on the basis of regression data, pogliani factor q and cross validation technique. the results are found to be useful in discussing the mechanism of drug–receptor interaction.
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کلیدواژه
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QSAR; Bcl-2; Bcl-w; Anti-apoptotic activity
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آدرس
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University of Allahabad, Department of Chemistry, QSAR Research Laboratory, India, University of Allahabad, Department of Chemistry, QSAR Research Laboratory, India, University of Allahabad, Department of Chemistry, QSAR Research Laboratory, India, University of Allahabad, Department of Chemistry, QSAR Research Laboratory, India, University of Allahabad, Department of Chemistry, QSAR Research Laboratory, India
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Authors
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Archana
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