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Synthesis of some new substituted iodoquinazoline derivatives and their antimicrobial screening
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نویسنده
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Alafeefy Ahmed M. ,El-Azab Adel S. ,Mohamed Menshawy A. ,Bakhat Mohamed Afroz ,Abdel-Hamid S. G.
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منبع
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journal of saudi chemical society - 2011 - دوره : 15 - شماره : 4 - صفحه:319 -325
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چکیده
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A new series of 6-iodo-2-thienylquinazolin-4(3h)-one and its fused heterocyclic analogs were prepared and screened for their antimicrobial activity. compounds 4, 8, 14 and 24 showed remarkable broad spectrum antimicrobial activity. the fused heterocycles, 1,2,4-triazino[3,4-c] quinazoline, benzimidazo[1,2-c]quinazoline and quinazoline-bearing thiazolidinone moiety proved to contribute for antimicrobial activity. the detailed synthesis and their antimicrobial screening are reported.
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کلیدواژه
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Synthesis; 6-Iodo-2-thienylquinazolin- 4(3H)-one; Antimicrobial screening
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آدرس
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AlKharj University, College of Pharmacy, Department of Pharmaceutical Chemistry, Saudi Arabia, King Saud University, College of Pharmacy, Department of Pharmaceutical Chemistry, Saudi Arabia, AlKharj University, College of Pharmacy, Department of Pharmaceutical Chemistry, Saudi Arabia, AlKharj University, College of Pharmacy, Department of Pharmaceutical Chemistry, Saudi Arabia, AlKharj University, College of Pharmacy, Department of Pharmaceutical Chemistry, Saudi Arabia
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Authors
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