SYNTHESIS AND MICROBIOLOGICAL TESTING OF SOME NEW DERIVATIVES OF COMPOUNDS CONTAINING ACTIVE METHYLENE GROUP

2-amino-4- (substituted phenyl)-7,7-dimethyl- (substituted phenyl)-4,6,7,8-tetrahydro 1-quinoline-3-carboxylic acid amide, 2-amino-1- (substituted phenyl)-7,7-dimethyl (substituted phenyl)-4,6,7,8-tetrahydro–1h-quinoline-3-carbonitrile-5-one, 5,10-di[ (substituted phenyl)-8,8-dimethyl-5,8,9,10-tetrahydro-3h, 7h-pyrimido (4, 5-b)]quinoline-4, 6-dione, 4- (substituted phenyl)-3,4,5,6,7, 8-hexahydro-1hquinoline-2-thione, 5-(substituted phenyl)-1,2,4,5,6,7,8,9-octahydro benzo[f] [1,2,4]triazepine-4-one and5-(substituted phenyl)-1,2,4,5,6,7,8,9-octahydro-1h-benzo[f][1,2,4]triazepine-3-thione were synthesized.the microbiological testing of some of synthesized compounds showed that, some of the tested compounds having antibacterial and antifungal activity using cephalexine and nystaine as standard antibacterial and antifungal agents respectively.