Primary cutaneous CD8+ T-cell lymphoma

Primary cutaneous aggressive cd8+ t-cell lymphoma is an extremely rare entity with distinct clinicopathological features. we report a case of a 28-year-old man that clinically presented with an ulcerated nodule on his trunk and extremities. histopathologic sections showed an ulcerated epidermis with a diffuse lymphocytic infiltrate in the superficial dermis with focal epidermotropism. immunohistochemically, the tumor cells were positive for cd3 and cd8 but negative for cd4, cd20, cd30 and cd56. granzyme b was positif. he received uvb therapy subsequently associated to interferon with an important regression of the nodules.