Serum Biochemical Change Induced by in vitro Sub Chronic Mercury Chloride in Yellowfin Sea Bream (Acanthopagrus latus)

Biochemical parameters are indicators measured in a biological system which can be related to exposure to, or effects of, a contaminant compound. in current study some serum biochemical parameters were measured in order to investigate patterns of response and change caused by the mercury contamination in yellowfin sea bream. according to the lc50, five mercury treatment was selected. serum glucose was measured photometrically based on the quantification of nadh after a glucose oxidation catalyzed by glucose dehydrogenase. serum total protein levels were determined with bovine serum albumin serving as standard. values recorded for activity of total protein show high significance depletion (p<0.001) with mercury exposed. although glucose was increase in different treatment, but there was not find significant variation. results of the present investigation indicated that the sub- acute mercury concentrations tested is a toxic substance in yellowfin sea bream and may cause several changes in the serum biochemical parameters.