Optimal Control Strategy on Transmission Dynamics of HIV-HSV-II Coinfection Model

In this paper, optimal control problem is applied to human immunodeficiency viruses (hiv) and herpes simplex virus type 2 (hsv-2) coinfection model formulated by a system of ordinary differential equations. optimal control strategy was employed to study the effect of combining different intervention strategy on the transmission dynamics of hiv-hsv-ii coinfection diseases. the necessary conditions for the existence of the optimal controls were established using pontryagin’s maximum principle. optimal control system was performed with help of runge-kutta forward-backward sweep numerical approximation method. finally, numerical simulation illustrated that a combination of all controls is the most effective strategy to minimize the disease from the community.