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Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness
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نویسنده
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cavaliere c. ,aiello m. ,perri c.d. ,fernandez-espejo d. ,owen a.m. ,soddu a.
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منبع
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frontiers in human neuroscience - 2015 - دوره : 8 - شماره : JAN
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چکیده
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Progress in neuroimaging has yielded new powerful tools which,potentially,can be applied to clinical populations,improve the diagnosis of neurological disorders and predict outcome. at present,the diagnosis of consciousness disorders is limited to subjective assessment and objective measurements of behavior,with an emerging role for neuroimaging techniques. in this review we focus on white matter alterations measured using diffusion tensor imaging on patients with consciousness disorders,examining the most common diffusion imaging acquisition protocols and considering the main issues related to diffusion imaging analyses. we conclude by considering some of the remaining challenges to overcome,the existing knowledge gaps and the potential role of neuroimaging in understanding the pathogenesis and clinical features of disorders of consciousness. © 2015 cavaliere,aiello,di perri,fernandez-espejo,owen and soddu.
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کلیدواژه
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Brain; Coma; Consciousness; Diffusion tensor imaging; Tractography
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آدرس
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coma science group,cyclotron research center and neurology department,university and university hospital of liege,liege, Belgium, irccs sdn,istituto ricerca diagnostica nucleare,naples, Italy, neuroradiology department,national neurological,institute c. mondino,pavia, Italy, psychology department,brain and mind institute,university of western ontario,london,on, Canada, psychology department,brain and mind institute,university of western ontario,london,on, Canada, physics and astronomy department,brain and mind institute,university of western ontario,london,on, Canada
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Authors
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