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Arousal modulates activity in the medial temporal lobe during a short-term relational memory task
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نویسنده
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thoresen c. ,jensen j. ,sigvartsen n.p.b. ,bolstad i. ,server a. ,nakstad p.h. ,andreassen o.a. ,endestad t.
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منبع
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frontiers in human neuroscience - 2012 - شماره : JANUARY 2012 - صفحه:1 -9
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چکیده
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This study investigated the effect of arousal on short-term relational memory and its underlying cortical network. seventeen healthy participants performed a picture by location,short-term relational memory task using emotional pictures. functional magnetic resonance imaging was used to measure the blood-oxygenation-level dependent signal relative to task. subjects' own ratings of the pictures were used to obtain subjective arousal ratings. subjective arousal was found to have a dose-dependent effect on activations in the prefrontal cortex,amygdala,hippocampus,and in higher order visual areas. serial position analyses showed that high arousal trials produced a stronger primacy and recency effect than low arousal trials. the results indicate that short-term relational memory may be facilitated by arousal and that this may be modulated by a dose-response function in arousal-driven neuronal regions. © 2012 thoresen,jensen,sigvartsen,bolstad,server,nakstad,andreassen and endestad.
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کلیدواژه
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Amygdala; Arousal; fMRI; Hippocampus; Relational memory; Serial position effect; Short-term memory
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آدرس
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division of mental health and addiction,oslo university hospital,oslo, Norway, division of mental health and addiction,oslo university hospital,oslo,norway,institute of clinical medicine,university of oslo,oslo,norway,department of psychiatry and psychotherapy,charité universitätsmedizin,berlin, Germany, institute of clinical medicine,university of oslo,oslo, Norway, institute of clinical medicine,university of oslo,oslo, Norway, section of neuroradiology,department of radiology and nuclear medicine,oslo university hospital,oslo, Norway, section of neuroradiology,department of radiology and nuclear medicine,oslo university hospital,oslo, Norway, division of mental health and addiction,oslo university hospital,oslo,norway,institute of clinical medicine,university of oslo,oslo, Norway, institute of psychology,university of oslo,oslo, Norway
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Authors
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