encapsulation of coenzyme q10 by gelatin–basil seed mucilage using complex coacervation: optimization, physicochemical characterizations and milk fortification

Global concern about human health and the increase the prevalence of chronic diseases in recent years lead to growing appeals for nutritious and healthy compounds, such as coenzyme q10. susceptibility to heat and lipophilic properties of coenzyme q10 limit its utilization in food. encapsulation is a technology that protects bioactive ingredients from harsh environmental conditions and extends shelf life. the purpose of this study was to encapsulate coenzyme q10 using complex coacervation by gelatin–basil seed mucilage and characterize physical, thermal and chemical properties of produced microcapsules. response surface methodology was applied to determine the optimum level of the four formulation variables for maximum encapsulation efficiency, loading capacity and turbidity and minimum supernatant absorption. the optimum microcapsules had encapsulation efficiency of 83.69%, encapsulation load of 16.32%, turbidity of 0.979 and supernatant absorption of 0.227. the microcapsules were assessed by scanning electron microscopy, fourier transform infrared spectroscopy, and differential scanning calorimetry. the results of ftir confirmed the formation of coacervates. the thermogram of q10 loaded microcapsule melting point was not observed at its melting point (50°c) due to its solubility in the oil phase and appropriate entrapment. release behavior of q10 was studied by different mathematical models. microencapsulated q10 was used to fortify milk and the results showed that the developed protein-carbohydrate microcapsules can be applied for protection of hydrophobic compounds.