noise exposure effects on blood glucose, cortisol and weight changes in the male mice

Background: noise is one of the most important hazardous factors in industrial environments. noise has many important negative effects on health; it can cause damage auditory, visual, neurological and psychological and hormonal systems, and physiological and cognitive functions. objectives: the current study aimed to investigate the effects of noise exposure on changes in glucose and cortisol serum levels in adult male mice. methods: a total of 24 adult male mice were randomly divided into two experimental and one control groups. one of the experi- mental groups was exposed to a noise pressure level of 90 db played by cool edit software on a computer in a frequency range 700 - 5700 hz, and the other one was exposed to the same noise and received an injection of streptozotocin (60 mg/kg). the experimental groups were exposed to the noise for 30 days, eight hours per day. twenty-four hours after the end of the exposure period the fasting cortisol and glucose serum levels were measured in the mice of the three groups. results: the study results showed a significant difference in the level of glucose in non-diabetic and diabetic groups exposed to the noise, compared to the control subjects (p < 0.002). in addition, there was a significant difference in the level of cortisol in non-diabetic and diabetic groups exposed to the noise, compared to the control groups (p < 0.002). conclusions: the results showed that exposure to a 90 db noise can increase cortisol and glucose levels. hence, in work environments where people are exposed to noise, it is expected that such noises have a negative impact on them and the noise may increase cortisol and blood sugar levels.