مطالعه کلینیکی و تغییرات هماتو ـ هیستوپاتولوژیک کوکسیدیوزیس در بزغاله‌های بومی استان چهارمحال و بختیاری

Coccidiosis is one of the most important causess of enteritis in lambs and kids and can be responsible for diarrhea, weight loss and even death. in this study a total number of 7 kids native from a flock with range ages between 3 to 4 weeks old with history of depression, loss of appetite, dehydration, emaciation and bloody diarrhea were referred for diagnosis of the disease to clinic of faculty of veterinary medicine, islamic azad university of shahrekord. haematological changes included decrease in rbcs (3.5 ×106 /mm3), hb content (5.5 ± 0.3 g/dl) also reduction pcv% (21 ± 1.85 %) and leukocytosis (21.35±0.95 × 103 /mm3) with neutrophilia (69±4 %), lymphocytopenia (24±3 % ). at necropsy, gross lesion were observed mostly in the ileum, cecum and proximal colon. this lesions containing cerebriform pattern on the serosal surface of the intestine, severe and diffuse a lot of small whitish non- pedunculated nodules on the mucosal surface of jejunum and middle ileum with hemorrhage and severe hemorrhage on the mucosa of the cecum and proximal colon. microscopical study of ileum nodules revealed increased length of crypts, papillary hyperplasias of the mucosal epithelium, mild inflammatory reaction and presence of developmental stages of the eimeria in the hyperplastic enterocytes. microscopic examination of the intestine is required in order to determine how much damage has occurred, particularly in the areas between the white nodules. in conclusion coccidiosis control programme major importance in domestic animals.