evaluation of toxoplasma gondii antibodies in addicted and non-addicted women in zahedan, southeast of iran

Background: toxoplasma gondii might lead to behavioral changes in patients with toxoplasmosis. since addicts are considered as individuals with behavioral, social, and psychiatric changes, we need to evaluate the prevalence of toxoplasmosis in addicts.objectives: this crosssectional study was conducted to measure toxoplasma antibodies using the enzymelinked immunosorbent assay (elisa) in addicted women who were kept at the zahedan welfare center in 2018.patients and methods: ninetysix addicted women with highrisk behaviors and history of narcotic drug consumption as the case group and 96 nonaddicted women (without a history of narcotic drug consumption) as the control group participated in this study. they had no history of alcohol consumption. the type of consumed narcotic drugs and the way of the consumption of narcotic drugs were indicated in the participants. after taking blood samples and separating the sera, the opium rapid strips were used to confirm the addiction status of the participants. then, all sera were evaluated for toxoplasma igg and igm antibodies using elisa.results: all sera showed positive results for addition using opium rapid strips. the elisa results indicated that the seroprevalence of toxoplasma igm in addicted women was 0.96%. also, the seroprevalence of toxoplasma igg was identified as 37.5% in addicted women and 27.1% in the control group.conclusions:according to the low difference in the rate of toxoplasma igg between addicts and controls, and the low rate of toxoplasma igm, the relationship between addiction and toxoplasmosis was not proven in this study. presumably, different factors can be involved, so more studies are needed to elucidate the reasons for the high seroprevalence of toxoplasmosis in addicts.