determination of the energy windows for the triple energy window scatter correction method in gadolinium-159 single photon emission computed tomography using monte carlo simulation

Introduction: in radionuclide imaging, object scatter is one of the major factors leading to image quality degradation. therefore, the correction of scattered photons might have a great impact on improving the image quality. regarding this, the present study aimed to determine the main and sub-energy windows for triple energy window (tew) scatter correction method using the simind monte carlo simulation code in gadolinium-159 (gd-159) imaging. material and methods: the energy window was set for various main energy window widths (i.e., 10%, 15%, and 20%) and sub-energy window widths (i.e., 3 and 6 kev). siemens medical system symbia fitted with a high-energy collimator was used with gd-159 point source positioned at seven locations inside the cylindrical water phantom. a comparison was made between the true primary to total ratio (calculated by simind) and the primary to total ratio estimated using tew method. results: the findings of this study showed that 20% of the main energy windows with 3 and 6 kev sub-energy windows were optimal for the implementation of the tew method in gd-159. conclusion: according to the results, the optimal energy windows for gd-159 scintigraphy were the sub-energy windows of 3 and 6 kev. these findings could be helpful in the quantification of gd-159 imaging.