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A review of three systemic retinoids in dermatology: acitretin, isotretinoin and bexarotene
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نویسنده
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Mortazavi Hossein ,Aghazadeh Nessa ,Ghiasi Maryam ,Lajevardi Vahideh
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منبع
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iranian journal of dermatology - 2013 - دوره : 16 - شماره : 4 - صفحه:144 -158
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چکیده
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Retinoids are synthetic and natural analogues of vitamin a that have various effects on cellular differentiation, cellular proliferation, immune system, and embryonic development. the present study reviews the history of systemic retinoids in medicine, the structure of synthetic retinoids and their mechanisms. the main focus is on their biologic functions, clinical uses, and the adverse effects of isotretinoin, acitretin, and bexarotene representing the most commonly used first, second, and third generation systemic retinoids, respectively.
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کلیدواژه
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acitretin ,bexarotene ,etretinate ,isotretinoin ,retinoids
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آدرس
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tehran university of medical sciences tums, Autoimmune Bullous Diseases Research Center, Department of Dermatology, ایران, tehran university of medical sciences tums, Department of Dermatology, ایران, tehran university of medical sciences tums, Department of Dermatology, ایران, tehran university of medical sciences tums, Department of Dermatology, ایران
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Authors
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