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   An unusual presentation of diffuse large B-cell lymphoma: a case report of an ulcerative inguinal mass  
   
نویسنده nasiri soheila ,najar nobari niloufar ,zaresharifi shirin ,zaresharifi nooshin
منبع iranian journal of dermatology - 2023 - دوره : 26 - شماره : 3 - صفحه:143 -146
چکیده    B-cell lymphomas represent most non-hodgkin lymphomas (nhls) arising within lymph nodes, and about 27% of patients have extranodal involvement. primary cutaneous lymphoma is defined as malignant lymphoma limited to the skin at diagnosis. diffuse large b-cell lymphoma (dlbcl) is the most common form of nhl, accounting for over one-third of all lymphomas. primary cutaneous diffuse large b-cell lymphoma (pcdlbcl) is a type of non-hodgkin’s lymphoma with skin involvement as the first and only site of involvement. primary cutaneous diffuse large b-cell lymphoma typically presents as a rapid-growing, red or bluish nodule or tumor on the legs, though around 10–15% of patients present with lesions elsewhere. this case report illustrates a rare manifestation of pcdlbcl presenting as a non-healing, rapidly progressive ulcer in the groin area diagnosed based on histopathology and immunohistochemical expression. the patient was treated successfully with systemic chemotherapy. this report could have implications for clinicians to consider the diagnosis of pcdlbcl in patients with unusual, non-healing, chronic ulcers, especially in the elderly, despite the anatomic site of the lesions.
کلیدواژه diffuse large B-cell lymphoma ,lymphoma ,ulcer ,non-Hodgkin lymphoma ,skin neoplasms
آدرس shahid beheshti university of medical sciences, skin research center, Iran, iran university of medical sciences (iums), rasoul akram hospital, department of dermatology, Iran, shahid beheshti university of medical sciences, skin research center, Iran, guilan university of medical sciences, department of pathology, Iran
 
     
   
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