Efficacy of CICACTIVE® versus silver sulfadiazine 0.1% cream on facial wound healing in patients treated with Erbium-YAG resurfacing laser: A single-blind randomized clinical trial

In recent years, laser skin resurfacing (lsr) has become the treatment of choice for a variety of pathological skin conditions such as facial rhytids, photoaged skin and acne scarring 1. cicactive® (cica) gel (uriage, france) is a hydrocolloid gel which is composed of sodium alginate, hydroxyprolisilane, d-panthenol, comfrey great, zinc gluconate and uriage thermal water 30%. this agent, which is fragrance-free and hypoallergic, and has a high tolerance, encourages wound healing and renewal of damaged epidermis. the gel suits for treatment of skin damage caused by mechanical reasons or after medical/dermatological treatment. studies have shown that zinc gluconate accelerates keratinization and wound healing; however, its synergistic effect with d-panthenol enhances the latter function 2. d-panthenol is a variant of vitamin