Serum Angiotensin Converting Enzyme in Patients with Psoriasis

Background: controversial data concerning the elevation of serum angiotensin-converting enzyme in psoriasis are reported in the literature. in order to verify whether this abnormality exists in iranian patients, we performed this study. method: serum angiotensin-converting enzyme level was measured in 40 psoriatics. according to clinical forms of psoriasis, patients were further divided into three groups: common plaque type (n=24), pustular psoriasis (n=10) and erythrodermic psoriasis (n=6). results: serum angiotensin-converting enzyme shows some increase in patients with psoriasis; the greatest increase in serum angiotensinconverting enzyme level was observed in patients with erythrodermic psoriasis. conclusion: our results suggest that angiotensin-converting enzyme may have a role in the aetiopathogenesis of psoriasis but further studies are warranted to evaluate the possible role of this enzyme in psoriasis