Comparison of the Effects of Propofol and Midazolam Sedation on Post-dural Puncture Headache

Background: post-dural puncture headache (pdph) is a common side effect after spinal anesthesia. objectives: this study aimed to compare the sedative dose of propofol and midazolam in reducing headaches after spinal anesthesia. methods: in order to conduct this study, 80 candidates for spinal anesthesia were divided into two groups, a and b. both groups received spinal anesthesia with marcaine. in group a, propofol was infused slowly at a dose of 30 g per minute, and in group b, 1 mg midazolam was injected intravenously. in the two groups, the incidence and intensity of headaches were measured using the vas pain scale. data were analyzed using mann-whitney and t-tests at a significance level of 0.05.results: in this study, 65% (52) were male and 35% (28) were female. there was no significant difference between the two groups in terms of demographic information (p > 0.05). in the propofol group, the incidence and severity of headaches were significantly lower than in the midazolam group (p < 0.01). conclusions: this study’s results indicated that administering low-dose propofol as a sedative during spinal anesthesia may be more effective in reducing pdph than midazolam.