The Effect of Citalopram and Colonazpam on Burning Mouth Syndrome

Statement of problem: psychosocial factors are thought to play a role in burning mouth syndrome (bms) and several therapeutic approaches for bms are based on this consideration.purpose: this paper evaluated the efficacy of the combined systemic administration of citalopram and clonazepam, as anti-depressant and anti-anxiety drugs, in the management of burning mouth syndrome and reduction of the burning sensation.materials and method: in this cross-sectional study, 80 subjects suffering from idiopathic burning mouth syndrome were enrolled. the patients underwent a thorough clinical examination. oral symptoms before and after treatment were assessed using a visual analogue scale. the mean duration of burning in our patients was 7 months. systemic combination of citalopram (20 mg/daily) and clonazpam (0.25 mg/daily) was prescribed for all of them for 8 weeks. then, the data were analysed, using student’s t-test.results: of the 62 patients who completed the protocol, 38 reported complete remission of the oral burning sensation. however, 20 patients reported a little improvement, and four of them reported no improvement.conclusion: these data suggest that citaloperam with colonazpam is effective in patients with bms