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   the yin and yang of sodium lauryl sulfate use for oral and periodontal health: a literature review  
   
نویسنده sabri hamoun ,derakhshan barjoei mohammad moein ,azarm ali ,sadighnia negar ,shakiba reza ,aghebati ghazal ,hadilou negin ,kheiri parisa ,ghanbari fariba ,deravi niloofar ,mokhtari melika
منبع journal of dentistry, shiraz university of medical sciences - 2023 - دوره : 24 - شماره : 3 - صفحه:262 -276
چکیده    Sodium lauryl sulfate (sls) is an anionic surfactant, which has a wide range of usage in the health sector and in dental pharmaceutical products, especially in toothpastes. the objective of this review was to investigate the effects of sls containing dentifrices on oral and periodontal health, possible side effects, and its benefits. a thorough literature search was done using databases of pubmed and google scholar and finally, 40 articles were included in the study. this narrative review revealed the sources of discrepancy and conflicting results regarding the impact of sls on oral cavity as well as a lack of suffi-cient evidence in most topics. hence, the evidence suggests improved drug bioavailability when used as a solubilizer, improved plaque control, and reduction in bad breath. on the other hand, sls can serve as a risk indicator of prolonged oral wound healing time, recur-rent aphthous stomatitis.
کلیدواژه sodium lauryl sulfate ,oral medicine ,drug effects ,oral mucosa ,oral cavity ,periodontal health
آدرس university of michigan, dental school, dept. of periodontics and oral medicine, usa, shahid sadoughi university of medical sciences, student research committee,usern officeusern office, iran, rafsanjan university of medical sciences, student research committee, iran, tabriz university of medical sciences, student research committee, iran, mashhad university of medical sciences, school of dentistry, iran, mashhad university of medical sciences, school of dentistry, iran, tabriz university of medical sciences, student research committee, faculty of dentistry, iran, tabriz university of medical sciences, student research committee, faculty of dentistry, iran, mashhad university of medical sciences, dental school, dept. of pediatric dentistry, iran, shahid beheshti university of medical sciences, student research committee, school of medicine, iran, islamic azad university, tehran medical sciences branch, student research committee, dental faculty, iran
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