the association between burning mouth syndrome and level of thyroid hormones in hashimotos thyroiditis in public hospitals in shiraz, 2016

Abstract statement of the problem: burning sensation in hashimoto patient’s oral cavity is an unknown prevalent problem. purpose: this study aimed to evaluate the prevalence and intensity of burning mouth syndrome (bms) in patients suffering from hashimoto’s thyroiditis in all public hospitals in shiraz, 2016. materials and method: a total of 153 patients with hashimoto’s thyroiditis were selected based on simple random sampling. the initial level of thyroid stimulating hormone (tsh), anti-tpo (thyroperoxidase), anti-tg (thyroglobu-lin), free t3 (triiodothyronine) and free t4 (thyroxine) serum as the indices of hashimoto’s thyroiditis was assessed. the bms intensity was measured accord-ing to each patient's verbal or nonverbal expression about the pain experience based on visual analog scale (vas). results: based on the clinical evaluation and interview, only 19out of 153 cases (12%) reported bms. the mean bms was 3 based on vas. statistically signifi-cant association was detected between the level of tsh (p= 0.0001), anti-tpo (p= 0.035), anti-tg (p= 0.0001), free t3 (p= 0.0001), free t4 (p= 0.0001) indi-ces in patients with bms. significant association was also observed between the level of anti-tpo (p= 0.0001), anti-tg (p= 0.0001), free t3 (p= 0.0001) and tsh (p= 0.0001) indices and bms intensity. however, no significant association was found between the bms severity and free t4 (p= 0.056). conclusion: the level of tsh, anti-tpo, and anti-tg, free t3, and tsh indi-ces of hashimoto’s patients were associated with the presence and severity of bsm. however, free t4 level was only associated with the presence of bms and not the intensity.