evaluation of laboratory parameters and comorbidities as prognostic factors in patients hospitalized with covid-19 during the 2020 epidemic

Background and objectives :the aim of study was to evaluate laboratory parameters and comorbidities in patients with coronavirus disease 2019 (covid-19) and to investigate their prognostic value in hospitalized patients. methods :this retro/spective study analyzed data from 400 covid-19 patients admitted to golestan hospital, kermanshah, iran (2020). laboratory parameters in patients including cbc diff plt, esr, ldh, pt, ptt, inr, fibrinogen, crp, and d-dimer, o2-saturation and lung ct scan were examined. statistical analysis was performed using spss v.25. results :in the evaluation of 400 patients, 52 patients were clinically unstable and 348 patients were in stable condition. significant gender differences were observed in hb, plt, esr, and coagulation profiles (p < 0.05). d-dimer-negative patients had higher saturation levels (p = 0.009) patients with positive d-dimer had unstable conditions in terms of oxygenation inverse correlations were found between oxygen saturation and wbc, ldh, pt, ptt, and inr (p < 0.05). the relationship of each of the diseases associated with covid-19 with mortality rate, clinical condition of the patient and o2-saturation in pulse oximetry was investigated. the most important diseases that, if associated with covid-19, could make the patient's clinical condition more unstable was htn and cva. conclusions :these findings suggest that routine hematological and coagulation tests can aid in early risk stratification of covid-19 patients, particularly in resource-limited settings where advanced imaging is unavailable. we suggest that during infectious epidemics such as covid-19, people with underlying diseases such as htn, dm, and cva should be under active surveillance.