the prevalence and pattern of enterobacter antibiotic resistance in the patients admitted to imam reza hospital in kermanshah, iran (2016 - 2018)

Background: antibiotic resistance is spreading worldwide against the gram-negative bacteria that cause nosocomial infections. objectives: the present study aimed to determine the antibiotic resistance pattern of enterobacter isolated from the blood, urine, wound, and sputum samples of the patients referring to imam reza hospital in kermanshah, iran. methods: this descriptive, cross-sectional study was conducted on 649 patients with positive enterobacter cultures at imam reza hospital during 2016 - 2018. the isolates were obtained using laboratory tests based on the clsi protocol. in addition, the standard disc-diffusion method was used to assess antibiotic susceptibility. data analysis was performed in spss version 20. results: most cases of positive enterobacteriaceae were isolated from the patients admitted to the intensive care unit (35.6%) and emergency ward (21.9%), as well as the urine (51.6%) and sputum samples (20.5%), respectively. levofloxacin, ciprofloxacin, and imipenem were the most effective antibiotics against enterobacter with the susceptibility of 56.7%, 54.8%, and 53.3%, respectively. conclusions: according to the results, the antibiotic resistance of enterobacter to ampicillin and ceftriaxone was high, and these antibiotics must be used correctly and reasonably. furthermore, more epidemiological studies are required in iran to provide national programs for preventing the spread of antibiotic resistance.