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Dapsone in the treatment of pemphigus vulgaris: Adverse effects and its importance as a corticosteroid sparing agent
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نویسنده
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quaresma m.v. ,bernardes filho f. ,hezel j. ,peretti m.c. ,kac b.k. ,azulay-abulafia l.
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منبع
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journal brazilian annals of dermatology - 2015 - دوره : 90 - شماره : 3 - صفحه:S51 -S54
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چکیده
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Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis,which has a fatal course in a large number of untreated patients. systemic corticosteroid therapy is considered first-line therapy. adjuvant treatment with the goal of sparing corticosteroids include,among others,dapsone. this drug is not without side effects and its use requires clinical and laboratory control. we present a patient with pv initially managed with suboptimal dose of prednisone,evolving into drug-induced hepatitis after introduction of dapsone. © 2015 by anais brasileiros de dermatologia.
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کلیدواژه
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Dapsone; Hepatitis; Pemphigus; Prednisone
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آدرس
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instituto de dermatologia professor rubem david azulay,santa casa da misericórdia do rio de janeiro (idprda-scmrj),rio de janeiro,rj, Brazil, instituto de dermatologia professor rubem david azulay,santa casa da misericórdia do rio de janeiro (idprda-scmrj),rio de janeiro,rj, Brazil, instituto de dermatologia professor rubem david azulay,santa casa da misericórdia do rio de janeiro (idprda-scmrj),rio de janeiro,rj, Brazil, instituto de dermatologia professor rubem david azulay,santa casa da misericórdia do rio de janeiro (idprda-scmrj),rio de janeiro,rj, Brazil, instituto de dermatologia professor rubem david azulay,santa casa da misericórdia do rio de janeiro (idprda-scmrj),rio de janeiro,rj, Brazil, instituto de dermatologia professor rubem david azulay,santa casa da misericórdia do rio de janeiro (idprda-scmrj),rio de janeiro,rj,brazil,universidade do estado do rio de janeiro (uerj),rio de janeiro,rj, Brazil
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Authors
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