Eosinophilic fasciitis

Eosinophilic fasciitis is a rare sclerodermiform syndrome of unknown etiology. it is characterized by the thickening of the muscular fascia and subcutaneous tissue,with a variable infiltration of eosinophils. peripheral eosinophilia,poly or monoclonal hypergammaglobulinemia and increased erythrocyte sedimentation rate can be seen. clinical features begin acutely,with local edema and a painful and symmetrical stiffening of the limbs,progressing rapidly to fibrosis,which can limit joint movements. some cases have a history of strenuous physical exercise or trauma. the diagnosis is confirmed by a deep skin biopsy. glucocorticoids in high doses is the treatment of choice. we report a typical eosinophilic fasciitis case with peripheral eosinophilia and dramatic response to pulse therapy with methylprednisolone. ©2016 by anais brasileiros de dermatologia.