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a review of the biological roles of mir-4800; a novel tumor biomarker with therapeutic potential
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نویسنده
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khordadmehr monireh ,matin reyhaneh ,baradaran behzad ,baghbanzadeh amir ,jigari-asl farinaz ,katiraee farzad
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منبع
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pharmaceutical sciences - 2022 - دوره : 28 - شماره : 3 - صفحه:376 -382
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چکیده
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Micrornas (mirnas) are known as a group of short noncoding ribonucleic acids (ncrnas). mainly, they can manage gene expression at the posttranscriptional level in the essential biological and physiological functions. significantly, more than 50% of the discovered mirnas genes are placed in cancer‐related genomic regions, which can act as oncomir or oncosuppressor. in this regard, growing evidence recently demonstrated the deregulation of mir-4800 in human cancers and non-cancerous diseases. however, little information is available on the biological roles of mir-4800 in cancer initiation, development, and progression. here, we reviewed the targeting sites and biogenesis functions of the mir‐4800 family in physiological and pathological processes like human cancers, particularly with a particular focusing on the validated specific targets.
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کلیدواژه
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cancer progression ,microrna ,physiological function ,therapeutic aspect
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آدرس
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university of tabriz, faculty of veterinary medicine, department of pathobiology, iran, university of tabriz, faculty of veterinary medicine, department of pathobiology, iran, tabriz university of medical sciences, faculty of medicine, immunology research center, department of immunology, iran, tabriz university of medical sciences, immunology research center, iran, university of tabriz, faculty of veterinary medicine, department of pathobiology, iran, university of tabriz, faculty of veterinary medicine, department of pathobiology, iran
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پست الکترونیکی
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katiraee_f@yahoo.com
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Authors
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