dicaffeoylquinic acids from the aerial parts of artemisia ciniformis krasch. & popov ex poljakov

Background: artemisia ciniformis (a. ciniformis) belongs to the genus artemisia and grows at northeast of iran. the current phytochemical study was carried out on the most potent extract in cell-free antioxidant assays. methods: hydroethanolic extract of the aerial parts was fractionated using vacuum-liquid chromatography (vlc). the selected fraction from the previous cell-free antioxidant study was purified by semi-preparative hplc. the structures of isolated compounds were identified using one- and two-dimensional nmr and esims techniques. results: three identified compounds in this study were the known isomers of dicaffeoylquinic acid (dcq), including 3,5- dcq (isochlorogenic acid a), 3,4-dcq (isochlorogenic acid b) and 4,5-dcq (isochlorogenic acid c). conclusion: the outstanding free radical scavenging potential in the hydroethanolic extract of a. ciniformis might be partly related to the presence of isochlorogenic acid derivatives.