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A Review Study: Effect of Growth Factors on Human Mesenchymal Stem Cells Differentiation into Cartilage Tissue
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نویسنده
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Pourmollaabbassi Babak ,Hashemibeni Batool ,Esfandiari Ebrahim
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منبع
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anatomical sciences journal - 2015 - دوره : 12 - شماره : 4 - صفحه:183 -190
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چکیده
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Hyaline cartilage is a vascular and neural tissue with scanty chondrocytes and limited regenerative ability. after some serious injuries of the cartilage, healing process will take place through the formation of fibrocartilage structures. currently, tissue engineering and cell therapy are 2 interesting therapeutic fields dealing with regenerative medicine. in this regard, tissue regeneration has found mesenchymal stem cells (mscs) with self-renewal and multipotential abilities as the best candidates for this process. growth and differentiation of mscs are induced by growth factors. the purpose of this review article is to evaluate the effect of growth factors and their signaling pathways involved in differentiation of mesenchymal stem cells into chondrocytes in vitro conditions
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کلیدواژه
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Mesenchymal stem cell ,Growth factor ,Chondro cartilage ,Tissue engineering
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آدرس
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Islamic Azad University of Najafabad, School of Basic Engineering, Department of Tissue Engineering, ایران, isfahan university of medical sciences, School of Medicine, Department of Anatomical Sciences, ایران, isfahan university of medical sciences, School of Medicine, Department of Anatomical Sciences, ایران
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Authors
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