the levels of inflammatory markers (il-6, crp), homocysteine and lipid profile in hemodialysis patients, isfahan

Background: cardiovascular disease (cvd) and inflammation areamongthe mostcommoncauses of mortality in dialysis patients. factors such as chronic inflammation, dyslipidemia and elevated homocysteine levels may underlie the increased risk of cvd. objectives: this study aimed to investigate levels of inflammatory markers, homocysteine, lipid profile, wbc, and bmi levels in hemodialysis patients compared with the control subjects in isfahan. methods: a total of 32 hemodialysis patients and 32 healthy subjects were selected randomly and their serum levels of il-6, crp, homocysteine, and lipid profiles were measured. results: according to the results, most of the studied hemodialysis patients compared to the healthy subjects had non-normal amounts of il-6, crp, and homocysteine i.e., higher than healthy subjects (p < 0.05). cholesterol, hdl, and ldl were significantly lower than the healthy subjects (p < 0.05), while triglycerides and vldl levels showed no significant difference (p: 0.38 > 0.05). a significant difference of bmi was observed between the normal subjects and the patients; thus, this factor in patients was less than what was in the healthy group (p: 0.001 < 0.05). conclusions: the results demonstrated that in most patients the levels of factors il-6, crp, and homocysteine were abnormal compared to the healthy group. in addition, the risk of developing cardiovascular and inflammatory disease as well as dyslipidemia in these patients is higher than normal.